Abstract Approximately 20% of aged captive giant pandas (Ailuropoda melanoleuca) have cataracts that impair their quality of life.To identify potential biomarkers of cataract formation, we carried out a quantitative proteomics analysis of 10 giant pandas to find proteins differing in abundance between healthy and cataract-bearing animals.We identif
Promoting sustainable agriculture and improving nutrition are the main License Plate united nation sustainable development goals by 2030.New technologies are requested to achieve zero hunger, and genome editing technology is the most promising one.In the last decade, genome editing using the CRISPR/Cas system has attracted researcher as a safer and
A 70-year-old Japanese man undergoing remission induction therapy for acute monocytic leukemia (AML-M5b) developed Fat Burners fever and headache, and was started on antibiotics and liposomal amphotericin B (L-AMB).There was no improvement, and computed tomography and contrast-enhanced magnetic resonance imaging revealed acute rhinosinusitis and br
Abstract Recurrent DNA break clusters (RDCs) are replication-transcription collision hotspots; many are unique to neural progenitor cells.Through high-resolution replication sequencing and a capture-ligation assay in mouse neural progenitor cells experiencing replication stress, we unravel the License Plate replication features dictating RDC locati